3 monkeypox sub-clusters found in India: ICMR study | India News


NEW DELHI: The Indian Council of Medical Research has found three sub-clusters of monkeypox cases detected in India — first cluster of Kerala (n5) and Delhi (n2) is aligned with the USA-2022 ON674051.1; second cluster of Delhi (n3) is aligned with USA-2022 ON675438.1; and third which consists of the UK, US and Thailand.
According to the ICMR study, all the retrieved monkeypox virus (MPXV) sequences from India covering 90% to 99% of the genome belong to the A.2 lineage of clade IIb.
During July-August 2022, clinical specimens i.e., oropharyngeal swab (OPS), nasopharyngeal swab (NPS), lesion crust and lesion fluids of 96 suspected monkeypox cases were referred from 18 states and three Union Territories to ICMR-National Institute of Virology, Pune, for diagnosis.
The 10 monkeypox confirmed cases were — three males and two females from New Delhi with no international travel history; five males were from Kerala with travel history from UAE to India.
All the cases were immuno-competent with no comorbidities with their mean age 31 years and presented with short prodromal phase of fever, myalgia, vesiculo-pustular lesions primarily in genital area, face, trunk and extremities.





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